Yet the field needs more sceptical voices and Raza certainly provides this.Įach chapter of the book takes it name from one of the author’s patients or someone who died of cancer. Being a colleague of Siddhartha Mukherjee, who wrote The Emperor of All Maladies, Azra is following a tough act for writing a cancer book.
Raza treats patients with the preleukemic condition myelodysplastic syndromes ( MDS), as well as its subsequent malignancy acute myeloid leukemia ( AML), which develops in around one-third of MDS patients. Azra Raza, an oncologist and researcher at Columbia, who has written a scathing denunciation of her field in The First Cell. No one is more disappointed in the translational failure of cancer research than Dr. Unfortunately these intellectual achievements have not led to effective treatments for most cancers. The discovery of oncogenes and tumour suppressor genes in the 1970s revealed that cancer is ultimately a genetic disease. After DNA was established as the chemical basis of heredity, remarkable advancements were made in the field of cell biology.
Theodor Boveri’s finding that chromosome damage can cause uncontrolled cell proliferation and Peyton Rous’ discovery of a sarcoma virus were critical breakthroughs in early genetics research. The history of medicine is intimately linked to the study of cancer.
Note: I have a technical accompanying post on my other website which analyses trends in Canadian cancer statistics.
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